http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1056816-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76f19dde6b2d748d5de43a414f343578 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
| filingDate | 1975-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84bff0dd1edb52f8141360c1d2b080fe |
| publicationDate | 1979-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1056816-A |
| titleOfInvention | Process for the conversion of 6-aminopenicillanic acid (6-apa) in 7-aminodesacetoxycephalosporanic acid (7-adca) |
| abstract | ABSTRACT OF THE DISCLOSURE The present invention relates to a process for the conversion of 6-aminopenicillanic acid (6-APA) to 7-aminodesacetoxycephalosporanic acid (7-ACDA), the improvement comprises reacting one mole of a compound selected from the group consisting of alpha-chloro- and alpha-bromobenzyl penicillin-(s)-sulphoxide with from two to four moles of 3-trimethylsilyl-2-oxazolidinone (TMSO) at a temperature of between 60° and 120°C in an inert non-hydroxylic solvent and in the presence of thiourea and a compound selected from the group consisting of triethylamine, dimethylaniline, quinoline and picoline p-toluene sulfonate to obtain a solution, thereafter removing the solvent by evaporation, diluting the residue with water, adjusting the pH to 4.2, and isolating 7-amido-desacetoxycephalosporanic acid (7-ADCA). |
| priorityDate | 1974-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.