http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1056814-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a285d8ecd0184a7e5d89a1e4e07997 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 |
| filingDate | 1978-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71c068402b92610c2db54e80899c1a2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f77bff118cb6dcf1283edd09327363e7 |
| publicationDate | 1979-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1056814-A |
| titleOfInvention | Formyl-(p-acyloxyphenyl) acetamidocephalosporanic acid derivatives |
| abstract | AsSTRACT OF THE DISCLOSURE This specification discloses certain novel .alpha.-amino- or .alpha.-formyl-.alpha.-(p-acyloxyphenyl)acetamidocephalosporanic acids which are useful as antibacterial agents, and methods of making them. The novel cephalosporin derivatives of this invention comprise the D-(-) compounds of the formula I wherein Y i5 hydrogen or S-Het, in which Het represents a 5 or 6 membered heterocyclic ring containing 1 to 4 atoms selected from N, O or S, said heterocyclic ring being optionally sub-stituted by C1-C4 alkyl which may be optionally substituted by a carboxylic acid group or hydroxy, or alkoxyalkyl of up to 4 carbon atoms; R is hydrogen, C1-C10 alkyl optionally sub-stituted by carboxylic acid, or phenyl optionally substituted by C1-C4 alkyl, halogen, nitro, amino or trifluoromethyl; R' is hydrogen, hydroxy, C1-C4 alkyl, C1-C4 alkoxy or halogen, and pharmaceutically acceptable salts thereof, when substantially free of the L-(+) isomer, and the D-(-) compounds of the formula I(a) I(a) wherein Y is S-Het, in which Het is 1,2,3-triazol-5-yl, 1-N-methyl-tetrazol-5-yl or 2-methyl-1,3,4-thiadiazol-5-yl; R is hydrogen, C1-C10 alkyl optionally substituted by carboxylic -?-acid, or phenyl optionally substituted by C1-C4 alkyl, halo-gen, nitro, amino or trifluoromethyl, R' is hydrogen, hydroxy, C1-C4 alkyl, C1-C4 alkoxy or halogen, ana pharmaceutically acceptable salts thereof, when substantially free of the L-(+) isomer. |
| priorityDate | 1974-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.