Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C33-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-095 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-26 |
filingDate |
1975-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1979-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64cbb8e0487acecf71ee9eb3d5757cb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba43ba9e23b2f0f710b290b6ef32301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5ec7767794f5456ecd4b74a4f2e614 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f824b59254e0cc8097b130cd56ad432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77c52153a7eebf3225efa9230a044ca6 |
publicationDate |
1979-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-1054626-A |
titleOfInvention |
Phenylbutanol derivatives, processes for their preparation and compositions containing them |
abstract |
ABSTRACT OF THE DISCLOSURE Phenylbutanol derivatives o the formula Z-C(CH3)(OH)-CH2-Y wherein Z is 4-biphenyl or 4-phenoxyphenyl wherein the phenoxy group is unsubstituted or substituted by F, Cl or Br and Y is COOR2 or CH2OR3 wherein R2 is H or alkyl of 1 to 6 carbon atoms and R3 is H or alkanoyl of 1 to 6 carbon atoms, and their physioiogically acceptable salts, possess anti-inflammatory activity and are produced by (2) treating with a solvolyzing agent a compound of the formula Z-C(CH3)(OH)-CH2-W or Z-CX(CH3)-CH2-Y wherein W is functionally modified carboxy or methylol group different from Y and X is Cl, Br or a or a functionally modified hydroxyl groups or (b) reducing a compound otherwise corresponding to a desired final product but having instead of one of the hydrogen atoms a group which can be reduced or replaced by a hydrogen atom; or (c) oxidizing a compound otherwise corresponding to a desired final product but lacking the tertiary hydroxyl group; or (d) converting a compound otherwise corresponding to a desired final product wherein Z is a 4-phenoxyphenyl group but having instead a 4-OH-, Cl-, Br- or I-substituted phenyl group into a desired final product; or (e) diazotizing a compound otherwise corresponding to a desired final product wherein Z i8 a haIogen-substituted 4-phenoxyphenyl group but having an -NH2-substituted phenoxy group and reacting the resulting diazonium salt with a halogenating agent. |
priorityDate |
1974-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |