| abstract |
ABSTRACT OF THE DISCLOSURE The invention relates to novel biologically active tetracyclic piperidino derivatives of the general formula: I as well as the pharmaceutically acceptable salts and nitrogen oxides (N2) thereof, in which: R1 and R2 represent hydroxy, halogen, alkyl (1-6 C), alkoxy (1-6 C), alkylthio (1-6 C) or trifluoromethyl, R3 stands for hydrogen, alkyl (1-6 C) or aralkyl (7-10 C), r and r' stand for the number 0, 1 or 2, X represents oxygen, sulphur, the group or methylene and R4 stands for hydrogen or alkyl (1-4 C). The novel compounds of the present invention are useful as tranquillizers which exhibit an anti-depressant effect. |