http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1052810-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d6256baf554e46784d8daa478a2ddc6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-86 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-091 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 |
filingDate | 1975-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1979-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13b2e68ee8b41e026dc1a023674f603f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6592eea4f06b6f90cbfd092ca91f5651 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b97240605aac0fc09734d064bba1e11d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2782ca38c76c40a624465e9ae455a72f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b9baa07c7489f66ba938b8e5ad85ab0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9ac0ebaadb36aa21f69a155a774cbf7 |
publicationDate | 1979-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1052810-A |
titleOfInvention | .omega.-(N-ACYLAMINO) ALKYLPHOSPHORYL ETHANOLAMINES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USES |
abstract | ABSTRACT OF THE DISCLOSURE New .omega.-(N-acylamino)alkylphosphoryl ethanolamines and their pharmaceutically acceptable acid addition salts having superior renin-inhibitory activities, antihypertensive activities alkylphosphoryl ethanolamines are prepared by (1) reacting an .omega.-(N-acylamino) alkanol with a 2-(N-substituted amino)ethyl phosphate or its derivative, hydrolyzing the resulting product or splitting off the phosphoric acid-protective group of the result-ing product thereby to form an .omega.-(N-acylamino) alkyl-2-(N-substi-tuted amino) ethyl phosphate, and splitting off the amino-protective groups of the resulting phosphate, or (2) reacting an .omega.-(N-acylamino) alkanol with a phosphorus oxyhalide, reacting the resulting .omega.-(N-acylamino)alkyl dichlorophosphate with a 2-(N-substituted amino) ethanol, hydrolyzing the reaction product to from an .omega.-(N-acylamino)alkyl 2-(N-substituted)ethyl phosphate, and splitting off the amino-protective groups of said phosphate. |
priorityDate | 1974-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.