http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1050970-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e42114d4d0f2966f76ba69072658e0f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 |
filingDate | 1975-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1979-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d38491532c3d7ae22b663a737c37b42c |
publicationDate | 1979-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1050970-A |
titleOfInvention | PROCESS FOR THE PRODUCTION OF 7-(D-(.alpha.-AMINO)-PHENYLACETAMIDO)-3-DESACETOXY-CEPHALOSPORANIC ACID |
abstract | ABSTRACT OF THE INVENTION The process comprises the following steps: - silylation is acetonitrile of 7-amino-3-methyl- 3-cephem-4-carboxylic acid (II) of formula: with a silyating agent chosen from the group comprising of hexaalkyldisi-lazane and N1,N2-bis-(trialkylsilyl)-urea in which the alkyl groups have from 1 to 6 carbon atoms, - addition of D-phenylglycinechloride hydrochloride in the presence of urea obtaining an acetonitrile solution of a condensation product og said silylated acid (II) with D-phenylglycinechloride hydrochloride, - hydrolysis of the said condensation product by adding water to the acetonitrile solution obtaining said product (I) dissolved in the said solution, - predpitation of the said product (I) to its isoelectric point, - separation of the said precipitated product (I), - restructuration of the separated product (I). |
priorityDate | 1975-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.