http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1050968-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7dfd84f9157ae12c41e319ec325338d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 |
| filingDate | 1975-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1dcea3cbf36c8e85cfd5e8c1a6e1bcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_626d6f3fe14142c9ecbbb2c5090068e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a57ba3a6280aadf2caec6abec92b6246 |
| publicationDate | 1979-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1050968-A |
| titleOfInvention | Process for the production of cephem compounds |
| abstract | ABSTRACT OF THE DISCLOSURE A process for the production of a cephem compound of the formula ( I) wherein R is a hydrogen atom; a free or protected amino group of the formula -NHA where A is a hydrogen atom or a known amino-protecting group subsequently cleavable from the amino group; a carboxyl or carboxylate group of the formula -COOB where B is a hydrogen atom or an organic or inorganic cation; a formamido group of the formula -NHCHO; or a free or protected hydroxyl group of the formula -OD -where D is a hydrogen atom or a known hydroxyl-protecting group cleavable from the hydroxyl group or is an alkanoyl group, aralkanoyl group or aroyl group which may be substituted with a halogen atom or nitro group; Rl is a hydrogen atom; a substituted or unsubstituted alkyl group; a substituted or unsubstituted aryl group; a substituted or unsubstituted alkoxyl group; a substituted or unsubstituted aryloxy group; a substituted or unsubstituted aralkyloxy group; a substituted or unsubstituted cycloalkyl group; a substituted or unsubstituted cycloalkenyl group; a substituted or unsubstituted alkylthio group; a sub-stituted or unsubstituted arylthio group; a substituted or unsubstituted heterocyclic thio group; cyano group; a substituted or unsubstituted heterocyclic group containing or not containing a condensed ring; or a substituted or unsubstituted aryl group containing a condensed ring: R2 is a hydrogen atom; a substituted or unsubstituted alkyl group; a substituted or un-substituted aryl group; a substituted or unsubstituted alkoxyl group; a substituted or unsubstituted aryloxy group; a substituted or unsubstituted aralkyloxy group; a substituted or unsubstituted cycloalkyl group; a substituted or unsubstituted cycloalkenyl group; a sub-stituted or unsubstituted alkylthio group; a substituted or unsubstituted arylthio group; a substituted or un-substituted heterocyclic thio group; cyano group; a substituted or unsubstituted heterocyclic group containing or not containing a condensed ring; a substituted or unsubstituted aryl group containing a condensed ring; a halogen atom; azido group; a dialkylamino group; a substituted or unsubstituted diarylamino group; a sub-stituted or unsubstituted alkoxycarbonyl group; or a substituted or unsubstituted alkanoyl group: or R1 and X2 taken together with the carbon atom attached to both R1 and R2 form a cyclic ring: or R1 and R2 taken together form an alkylidene or arylidene group R3 is a hydrogen atom; acetoxy group; azido group; cyano group; a sub-stituted or unsubstituted alkoxyl group; a substituted or unsubstituted aroyloxy group; a substituted or unsub-stituted aralkyloxy group; a substituted or unsubstituted alkylthio group; a substituted or unsubstituted arylthio group; a substituted or unsubstituted aralkylthio gruop; or a substituted or unsubstituted heterocyclic thio group: and M2 is an alkali metal cation, an ammonium cation or a hydrogen atom, which comprises reacting a compound of the formula ( II) wherein R1 and R2 are each as defined above, R' is the same as R except that R' does not denote the free amino or free hydroxyl group 9 and Ml is an inorganic or organic cation, with a 7-aminocephalosporanic acid derivative of the formula ( III) wherein R3 and M2 are each as defined in the above, in a homogeneous aqueous solution of these two reactants 9 to prepare a reaction product of the formula ( I') wherein R', R1, R2, R3 and M2 are each as defined in the above, and where R' denotes the protected amino or protected hydroxyl group, optionally removing the amino-protecting group A or the hydroxyl-protecting group D from the reaction product of the formula (I'). |
| priorityDate | 1974-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 220.