http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1050888-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-235 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60 |
| filingDate | 1974-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f82afdc19ae109ae68dd8afc949b471d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92b5dbdbb2968008aeb158620c8ee760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fef8c9cb766bafd47f19c127ed69696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fd2b94caaae9b163121788cb1e8bfb1 |
| publicationDate | 1979-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1050888-A |
| titleOfInvention | Histidine decarboxylase inhibitors |
| abstract | HISTIDINE DECARBOXYLASE INHIBITORS Abstract of the Disclosure Compounds having the general formula wherein R1 is OH or in which Y is lower alkyl or phenyl; R2 is substituted either at the 4 -position or at the 5 -position and is hydrogen, fluoro, bromo, chloro, hydroxy, lower alkyl or in which Y is lower alkyl or phenyl; R3 is chloro, bromo or lower alkyl; R4 is hydroxy, amino, low r alkoxy or in which Y is lower alkyl or phenyl-; R5 is hydrogen, fluoro, bromo, chloro, carboxyl, lower alkyl or in which Z is lower alkyl; and the nontoxic, pharmaceutically acceptable metal-salts of said compound in which R5 is carboxyl; and the pharmaceutically acceptable salts and esters thereof exhibit strong activities in inhibiting histidine decarboxylase and xanthine oxidase. One example is the compound of the formula |
| priorityDate | 1973-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.