http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1047483-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 |
| filingDate | 1975-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b02a87a80bc21709b13a832b580c9967 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54645d4f31a0f0b4d56fa76815ad22cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62eacb9299f5923b87f2ac0e4cd97ef8 |
| publicationDate | 1979-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1047483-A |
| titleOfInvention | PROCESS FOR PRODUCING 3-HEMISULPHATE-17.alpha.-HYDROXY STEROIDS |
| abstract | ABSTRACT OF THE DISCLOSURE A 3-hemisulphate sodium salt of a 17.alpha.-hydroxy steroid which is estrogenically effective, and having the general formula is produced by treating a 3-hydroxy-17-acyloxy steroid of the general formula with sulphur trioxide or a sulphur trioxide-containing agent in an organic nitrogen compound, preferably pyridine, and converting the resulting product into the corresponding sodium salt by treat-ment with an alkali, preferably sodium alcoholate or sodium hydrox-ide in a lower alcohol, with simultaneous saponification. In the above formulae R1 represents hydrogen, methyl or ethyl and R2 represents an acyl radical containing up to 15 carbon atoms, and the rings B and C can contain additional double bonds. For example, 17.alpha.-acetoxy-1,3,5(10)-estratrien-3-ol is treated with sulphur trioxide in the presence of pyridine, and the resulting product is treated with sodium methylate/methanol to produce 17.alpha.-estradiol-3-hemisulphate sodium. |
| priorityDate | 1974-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.