http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1042006-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b86dbdcfe153c2dfb874aff99d07177
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-20
filingDate 1978-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1978-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67b6c312341f51a44393be3c90a01dd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a6be8bb8bfe8bbe3bc0e3a73ceabd9
publicationDate 1978-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1042006-A
titleOfInvention Isoxazole derivatives
abstract Isoxazole Derivatives ABSTRACT OF THE DISCLOSURE This invention provides 1,2-benzisoxazole derivatives of the formula: wherein R1 represents one or more substituents which are at any one or more of the available positions in the benzene ring and which are selected from one or more of the following atoms or groups; hydrogen, halogen, preferably chlorine or bromine, C1-4 alkyl, preferably methyl, C1-C4 alkoxy, preferably methoxy, nitro, and trifluoromethyl, and R2 is a substituent at the 5-, 6-, or 7- position of the 1,2-benzisoxazole nucleus and is one of the following: hydrogen, C1-4 alkyl, preferably methyl, carboxy C1-4 alkyl, preferably carboxymethyl, cyano C1-4 alkyl, preferably cyanomethyl or 1-cyanoethyl, -CH(R3)? COOH, -CH2?COOR3, and -CH(R3)?COOR3, where R3 is C1-4 alkyl; except that when R1 represents a hydrogen atom R2 is not hydrogen. Some of the compounds embraced by the above generic formula possess valuable pharmacological activity, while others are useful as intermediates in the synthesis in preparing pharmacologically active compounds.
priorityDate 1973-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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