abstract |
Abstract of the Disclosure This invention relates to the novel compounds 3',5,7-trihydroxy-4',6-dimethoxy-isoflavone, 3',5,7-trihydroxy-4',8-dimethoxy-isoflavone and 3'7-di hydroxy-4',6,8-trimethoxy-isoflavone which are power-ful inhibitors of catechol-O-methyl transferase (COMT) (2.1.1.6) and to their production by fermentation of Actinomyces roseolus. |