abstract |
SYK IMIDAZOPYRAZINE INHIBITORS. Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to inhibitors of Syk activity, comprising administering to such patients an amount of at least one chemical entity effective to reduce the signs or symptoms of the disease or disorder are provided. Methods for determining the presence or absence of Syk kinase in a sample are also provided. |