| abstract |
CHROMENE COMPOUND AND DERIVATIVES THEREOF. A compound is provided which has excellent S1P1 agonist action, and is particularly useful as an active ingredient for an agent to prevent and/or treat a disease induced by unwanted lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells . According to the present invention, a 2H-chromene compound or a derivative thereof which has an excellent S1P1 agonist action, and is particularly useful as an active ingredient of an agent to prevent and/or treat an infiltration-induced disease of unwanted lymphocyte or a disease induced by abnormal proliferation or accumulation of cells may be provided. The 2H-chromene control and a derivative thereof which are the compounds of the present invention have an S1P1 agonist action, and can be used particularly for the prevention and/or treatment of an undesirable lymphocyte infiltration induced disease or a disease induced by abnormal proliferation or accumulation of cells. |