| abstract |
pyridine-3-carboxylated derivative. provide a new inhibitor of jak3 that is useful as a preventive and / or therapeutic agent for graft versus host disease and rejection (gvhd) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, sjögren syndrome, behcet disease, type i diabetes mellitus, autoimmune thyroid, idiopathic thrombocytopenic purpura, ulcerative colitis, crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, ieukemia and the like. the pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof. |