abstract |
Amide Compound [Problems] The present invention provides a compound which is useful as an active ingredient in a pharmaceutical composition, for example, a pharmaceutical composition for treating chronic renal failure and / or diabetic nephropathy. [means for resolution] The present inventors have conducted extensive studies on a compound with ep4 receptor antagonist activity, and confirmed that the amide compound of the present invention has ep4 receptor antagonist activity and thus concluded the present invention. the amide compound of the present invention has ep4 receptor antagonist activity and may be used as an active ingredient in a pharmaceutical composition to prevent and / or treat various ep4 receptor related diseases, for example chronic renal failure and / or diabetic nephropathy, and similar conditions. |