http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0903700-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e23bee70d08567d9afc917a29989f118 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M31-00 |
| filingDate | 2009-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39238655f7acf52df1dd074890654716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dde989bf932d55288770307c7fbc855a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb6caf31109313112adf6f510b76f010 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3978d2f60d50f3a8f6b87e3c30469d40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5f54af82f39e22be4301a05bb892861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdc7592123eb0c4a8f5b85ed0cc6df39 |
| publicationDate | 2012-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0903700-A2 |
| titleOfInvention | magnetic antibiotic vectorization system for treatment of helicobater pylori infections |
| abstract | MAGNETIC SYSTEM FOR VECTORIZING ANTIBIOTICS FOR TREATING INFECTIONS BY HELICOBACTER PYLORI. Patent for the invention of a magnetic system for the vectorization of antibiotics for the treatment of Helicobacter pylori infections. The system consists of magnetite microparticles coated with a gastroresistant polymer and containing antibiotics. Current therapy has several limitations. As an alternative therapy, the invention proposes the vectorization of the antimicrobial by means of superparamagnetic particles guided through an external field towards the site of action. Additionally, the magnetic vectoring system allows to increase the permanence of the medication at the action site. The proposed system is based on the oral administration of the antibiotic complexed to the magnetic vector by means of polymeric structure forming microparticles with magnetic response. An external magnet located in the abdomen must be used in order to promote the permanence of the particles in the place of interest. The attractive force exerted by the magnetic field is used to bring the microparticles closer to the mucosal surface where the pH gradient is high, which will favor the degradation of the polymer and consequent release of the drug closest to the bacteria. This technique is able to promote the use of lesser amount of drug and / or frequency of administration. |
| priorityDate | 2009-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.