http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0823074-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbf5097f39b7e121fa7ae77652628801 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14143 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-866 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate | 2008-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_586a0369bb81dbb448dfd02d23d2277b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_238dba80cf7e11a943a80d3ff487be42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c855d13adbaf603022a2fb06cd65959 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fe6ed6f6ec0941fc1d99cc465aab7de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_606c8a4ffc6362f1e92b8f3e9cc9d824 |
| publicationDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0823074-A2 |
| titleOfInvention | method for developing polynucleotide regulatory sequences, polynucleotide regulatory sequences, use of polynucleotide regulatory sequences, expression vector, transformed or transfected cells, transfected insect larvae, method for producing recombinant proteins, use of expression vector, and use of insect larvae |
| abstract | METHOD FOR DEVELOPING POLYNUCLEOTIC REGULATORY SEQUENCES, POLYNUCLEOTIC REGULATORY SEQUENCES, USE OF POLYNUCLEOTIC REGULATORY SEQUENCES, VECTOR OF EXPRESSION, TRANSFECTED, TRANSFECTED, TRANSFECTED, TRANSFECTED, CELLS, TRANSFECTED, CELLED The present invention provides insect-derived promoters for the expression of foreign proteins in insect cells. In the invention, polynucleotide regulatory sequences, which direct the expression of major insect proteins (hexamerins) at specific stages of larva evolution, were isolated from insects (Trichoplusia ni). These polynucleotide regulatory sequences promote the stronger expression of foreign gene in the baculovirus system when compared to that of the conventional polyhedrin promoter. In addition, the combination of the new larva-derived promoters of the invention with the pL promoter increased levels of baculovirus expression by up to 61% -375% (depending on the time of infection) compared to conventional baculoviruses used in the biotechnology industry. The pB2 promoter also directs gene expression in premature moments when compared to the polyhedrin promoter, this aspect being a great advantage for the correct protein. |
| priorityDate | 2008-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.