| abstract |
triazolsubstituted arylamide derivatives and their use as p2x3 and / or p2x2 / 3 purinergic receptor antagonists The present invention relates to the compounds of formula (i): i; or a pharmaceutically acceptable salt thereof, wherein, r 1 is optionally substituted triazolyl, and r 2, r 3, r 4, r 5, r 6, r 7 and r 8 are as defined herein. Also disclosed are methods of using the compounds to treat diseases associated with p2x3 and / or p2x2 / 3 receptor antagonists and methods of making the compounds. |