| abstract |
use of nacetillactosamine-containing oligosaccharides for maturation of immune responses in neonates. The present invention relates to the use of an oligosaccharide selected from the group consisting of lacto-n-tetraose, lacto-n-neo-tetraose, lacto-n-hexaose, lacto-n-neohexaose, para-lacto-n-hexaose. , for -lacto-n-neoexaose, lacto-n-octaose, lacto-n-neooctaose, iso-lacto-n-octaose, para-lacto-n-octaose and lacto-n-decaosein in the manufacture of a medicament for or a therapeutic nutritional composition for children to modulate immune responses in a neonatal child. The invention extends to the use of such an oligosaccharide to modulate a neonatal infant's immune system to promote the development in the early weeks of a child's life of a beneficial intestinal microbiota comparable to that found in breast-fed children and to reduce the risk of development. subsequent allergy in the child. |