| abstract |
compounds as adenosine receptor antagonists until these compounds correspond to formula (I), wherein: R1 represents an aryl or heteroaryl group optionally substituted by one or more substituents selected from a group consisting of optionally substituted linear or branched halogen atoms by straight or branched lower alkyl, cycloalkyl, hydroxy optionally substituted by alkoxy, cyanide, or -CO2 'where r' represents a hydrogen atom or an optionally substituted straight or branched lower alkyl group; R represents a group selected from: a) a straight or branched lower alkyl group substituted by one or more carboxylic groups (cooh) and optionally substituted by one or more halogen atoms; b) a cycloalkyl group substituted by one or more carboxylic groups (-cooh) and optionally substituted by one or more halogen atoms; c) a straight or branched alkylcycloalkyl or cycloalkyl cycloalkyl group substituted by one or more carboxylic groups (coo) and optionally substituted by one or more halogen atoms. formula (i). |