| abstract |
derivatives of 7-alkynyl -1,8-naphthyridones, their preparation and their application in therapy the present invention refers to the compounds corresponding to formula (1): in which: r1 and r2 represent, independently of each other: an atom of hydrogen, a C1-C7 alkyl group optionally substituted by one or more alkoxy groups, R3 represents a C1-C7 alkyl group; r4 represents a hydrogen atom, a c1-c4 alkyl group; y represents an alkoxy group at c1-c4, a group -nrr ', -o (ch2) n- c (o) - nrr', in which rer 'are as defined below and n is an integer equal to 1 or 2 ; r "represents a c1-c4 alkyl group; erer 'independently represents a hydrogen atom, a c1-c4 -co-alkyl group or a -coor group", in which r ", as defined above. process of preparation and application in therapy. |