http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0813695-B8
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9880469dc8f12dad7c3ad95c6ab31fe |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2008-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50c1eae93911e6081228e6ca236d7d80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5f1fd744c66d5624876c952731cf091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa2bcaf4debf960fa529e1cf1ad4798 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66c5025f3060d60422f372c7697f4bb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_469ff603adaeaeb3288dd8645c9cf054 |
| publicationDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0813695-B8 |
| titleOfInvention | fused heteroaryl pyridyl and phenyl benzenesulfonamide compounds, composition, method of modulating ccr2 function, uses of compounds, and crystalline form |
| abstract | fused heteroaryl pyridyl and phenyl benzenesulfonamide compounds, composition, method of modulating the ccr2 function, uses of said compounds and crystalline form. compounds are provided that act as potent ccr2 receptor antagonists. the compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for treating ccr2 mediated diseases, and as controls in assays for identifying ccr2 antagonists. a compound of the formula (I) or a salt thereof: wherein r1 and r2 are each independently hydrogen, c1-8 alkyl, -cn, or c1-8 haloalkyl, provided that at least one of r1 or r2 is different from hydrogen each r3 is independently, r4 is hydrogen; r5 is halogen or C1-8 alkyl; r6 is hydrogen; x1 is cr7, n or no; x2 and x4 are n or no; x3 is cr7; x6 and x7 are each independently selected from cr7 , n and no; each r7 is independently selected from the group consisting of hydrogen, halogen, c2-8 substituted or unsubstituted alkyl, c2-8 substituted or unsubstituted alkenyl, c2-8 substituted or unsubstituted alkynyl, -cn, =o , -no2 , -or6, -oc(o)r8, -co2r8, -c(o)r8, -c(o)nr0r8, -oc(o)nr9r8, -nr10c(o)r8, -nr10c(o) nr9r8, -nr9r8, -nr10co2r8, -sr8, -s(o)r8, -s(o)2r8, -s(o)2nr9r8, -nr10s(o)2r8, c5-10 substituted or unsubstituted aryl, heteroaryl substituted or unsubstituted 5 to 10 membered and substituted or unsubstituted 3 to 10 membered heterocyclyl. |
| priorityDate | 2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.