| abstract |
pharmaceutical composition provide a pharmaceutical preparation which exhibits satisfactory dissolution property over a wide pH range. the pharmaceutical composition is characterized by containing (a) n1-(5-chloropyridin-2-yl)-n2-((1s,2r4s)-4[(dimethylamino)carbonyl]-2{[(5-methyl-4,5) ,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamine, representing by formula (1), a pharmacologically acceptable salt thereof, or a hydrate of any of these, and (b) one or more species selected from the group consisting of a sugar alcohol and a hydrodilation additive. |