http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0804121-A8
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a693232b92910547c898db10feb83fef |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate | 2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38d1c94086189f8abe56b3c064fffa3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27c1cc14bbcdd5acb17e2af78ba38315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5985703711c9b357d6fc71547a333900 |
| publicationDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0804121-A8 |
| titleOfInvention | methods for resolving 4- [4- (dimethyl-amino) -1- (4'fluoro-phenyl) -1-hydroxy-butyl] -3- (hydroxy-methyl) -benzonitrile as a racemic or non-racemic mixture of enanciomers in their isolated enanciomers and for the manufacture of escitalopram |
| abstract | methods for resolving 4- [4- (dimethyl-amino) -1- (4'-fluoro-phenyl) - 1-hydroxy-butyl] -3- (hydroxy-methyl) -benzonitrile as a racemic or non- racemic analysis of enanciomers in their isolated enanciomers and for the manufacture of escitalopram. this patent describes a method for the resolution of 4- [4- (dimethyl-amino) -1- (4'-fluoro-phenyl) -1-hydroxy-butyl] -3- (hydroxy-methyl) -benzonitrile as a mixture racemic or non-racemic enanciomers in their isolated enanciomers, the aforementioned method comprising the steps of fractionally crystallize 4- [4- (dimethyl-amino) -1- (4'-fluoro-phenyl) -1-hydroxy-butyl] - 3- (hydroxymethyl) -benzonitrile as a salt with the (+) - (s, s) or (-) - (r, r) -enanciomer of o, o'-di-p-toluoyl-tartaric acid in a solvent system comprising 1-propanol, ethanol or acetonitrile. |
| priorityDate | 2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.