http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0804121-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate | 2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc8d157d2590d2a5d3f198ebd9720f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6a5080b904c08c671bbb9f32f3370a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd364dac7327c18dda6795f9c6b2ecbb |
| publicationDate | 2009-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0804121-A2 |
| titleOfInvention | methods for the resolution of 4- [4- (dimethylamino) -1- (4'-fluoro-phenyl) -1-hydroxy-butyl] -3- (hydroxymethyl) -benzonitrile as a racemic or non-racemic mixture. of enanciomers in their isolated enanciomers and for the manufacture of escitalopram |
| abstract | METHODS FOR SOLVING 4- [4- (DIMETHYL-AMINO) -1- (4'-FLUORO-PHENYL) - 1-HYDROXY-butyl] -3- (HYDROXY-METHYL) -BENZONITRIL AS A RACEMIC OR NOT RACEMIC OF ENANCIEMEROS IN ITS ISOLATED ENANCIEMERS AND FOR MANUFACTURE OF ESCITALOPRAM. This patent describes a method for the resolution of 4- [4- (dimethylamino) -1- (4'-fluoro-phenyl) -1-hydroxy-butyl] -3- (hydroxymethyl) -benzonitrile as a mixture racemic or non-racemic of enanciomers in their isolated enanciomers, said method comprising the steps of fractionally crystallizing 4- [4- (dimethylamino) -1- (4'-fluoro-phenyl) -1-hydroxy-butyl] - 3- (hydroxymethyl) benzonitrile as a salt with the O, O'-di-p-toluoyl tartaric acid (+) - (S, S) or (R, R) -enanciomer in a solvent system comprising 1-propanol, ethanol or acetonitrile. |
| priorityDate | 2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.