abstract |
new benzamide derivatives as bradykinin antagonists. the present invention relates to novel phenylsulfamoylbenzamide derivatives of formula (I), wherein r1-r5 are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are antagonists selective bradykinin b1, processes for producing these compounds, pharmaceutical compositions containing them, and their uses in the therapy or prevention of painful and inflammatory conditions. |