| abstract |
Patent of Invention: "USE OF POLYLES TO OBTAIN STABLE POLYPHORPHAL FORMS OF RIFAXIMIN". The present invention relates to polyols which stabilize the polymorphic form of rifaximin, in particular the beta form. When polyols having at least two hydroxy groups are added to the rifaximin powder, the beta polymorph is stable and remains stable over time, regardless of ambient humidity. In this invention, a method for preparing formulations consisting of pure and stable polymorph forms capable of producing a pharmaceutical product is described. |