| abstract |
COMPOUNDS AND COMPOSITIONS AS HEDGEHOG MODULATORS. The present invention relates to a method for modulating hedgehog signaling pathway activity. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes, such as loss of Ptc function, hedgehog function gain, smoothened function gain or Gil function gain, which comprises: contacting a cell with a sufficient amount of a compound of formula I. |