abstract |
PROCESS FOR PRODUCTION OF A COMPOSITION, PROCESS FOR PREPARING A MEDICINAL PRODUCT, COMPOSITION OBTAINED BY THIS PROCESS, USE OF A COMPOSITION, AND DISPOSAL. A process for producing a composition comprising a water-insoluble paracetamol or NSAID is described with the steps of: a) providing a mixture comprising i) a water-insoluble paracetamol or NSAID, ii) a water-soluble carrier and iii) a solvent for each of paracetamol or NSAID and the carrier, and (b) spray drying the mixture to remove the solvent or each solvent to obtain a substantially solvent-free nanodispersion of the paracetamol or NSAID in the carrier. |