| abstract |
REGOSOSLECTIVE SYNTHESIS OF BENZIMIDAZOIS AND AZABENZIMIDAZOIS CATALIZED BY PALĂDIO. The present invention relates to a process for regioselective synthesis of compounds of formula (1), wherein RO; Ri; R2; R3; R4; R5; There; A2; A3; A4, O and J have the meanings indicated in the claims. The present invention provides a direct palladium catalysed regioselective process for a wide variety of the symmetric multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula (1) starting from 2-halo-nitroarenes and substituted amides with N, useful for the production of pharmaceutical substances, diagnostic agents, liquid crystals, polymers, herbicides, fungicides, nematicides, parasiticides, insecticides, acaricides and anthropodicides. |