| abstract |
GEL COMPOSITION FOR TRASNDERMIC RELEASE OF PHARMACEUTICAL DRUG ROPINIROL, SINGLE DOSAGE CONTAINER AND MULTIPLE DOSAGE CONTAINER. The present invention comprises pharmaceutical drug release compositions of an indolone (e.g. ropinirol) or a pharmaceutically acceptable salt thereof. The composition may, for example, be a gel suitable for transdermal application. The compositions of the present invention typically comprise a hydroalcoholic carrier, one or more antioxidants, in one or more buffering agents, where the gel ph is usually between about ph 7 and about ph 9. The compositions may include additional components, for example For example, the hydroalcoholic carrier may also comprise additional solvents, antioxidants, co-solvents, penetration enhancers, buffering agents, and / or gelling agents. The compositions may be used for the treatment of various neurological disorders. |