| abstract |
NAPHALENE ARILSULFONIL DERIVATIVES AND USES OF THESE. The application relates to compounds of formula I: or pharmaceutically acceptable salts thereof, wherein: m is from 0 to 3; q is from 0 to 3; Ar is optionally substituted aryl or optionally substituted heteroaryl, R1 and R7 each independently is halo, alkyl, halalkyl, alkoxy, hydroxy, heteroalkyl, cyano, -S (O) t-Ra, -C (= NRbRc, -SO2-NRbRc , -N (Rd) -C (= O) -Re, or -C (= O) -Rf, where t is 0 to 2, Ra, Rb, Rc, Rd and Rd and Re each independently is hydrogen or alkyl, and Rf is hydrogen, alkyl, alkoxy or hydroxy (II) n is from 1 to 3. The compounds are 5-Hydroxytryptamine 6 and 2A receptor modulators. and methods for using compounds of formula I. |