| abstract |
PHENYLPENTADIENOIL DERIVATIVES AND ITS USE AS PAR ONE ANTAGONISTS. The present invention relates to compounds of formula wherein R 1 and R 2 are the same or different, represent a hydrogen or halogen atom, CN or NO 2, with R 1 and R 2 not represented hydrogen simultaneously, m represents 1 or 2, n represents 0, 1 or 2R3 represents phenyl whether or not substituted by one or more residues chosen from halogen, hydroxyl or C1-C6 alkyl; C 2 -C 6 alkyl substituted or unsubstituted by one or more residues chosen from halogen or hydroxyl; cycloalkyl; pyridine; thiophene; pyrrol substituted or unsubstituted by C1-C6 alkyl; thiazole or furan; or therapeutically acceptable salts or solvates thereof. |