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filingDate 2007-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f73e9e66812eb70a1785dcecb23198de
publicationDate 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0713565-B8
titleOfInvention process for manufacturing a solid oral dosage form
abstract pharmaceutical composition containing tetrahydrofolic acid. the present invention relates to solid pharmaceutical compositions, in particular oral contraceptives, comprising a progestogen such as drospirenone; an estrogen such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-methyl-(6s)-tetrahydrofolate; and at least one pharmaceutically acceptable carrier or excipient therefor. the compositions of the invention provide good stability of tetrahydrofolic acid upon storage while still ensuring rapid and reliable release of the estrogen and progestogen present in the composition.
priorityDate 2006-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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