| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad5feabfc7d04a11a2231a6ea875c53a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2007-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28c286e7df3fc73a2e8c3a61214df1bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eb90528687fd6dbca8722cb1e90bca0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efdea7b3f9cce2d6ac353c1275e4a6db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec8e2a28207fd3c9ca74293cc4c3a0f3 |
| publicationDate |
2012-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-PI0712850-A2 |
| titleOfInvention |
antibodies that recognize a cd-43 and cea carbohydrate-containing epitope expressed in cancer cells and their methods of use |
| abstract |
ANTIBODIES RECOGNIZING AN EPITOPO CONTAINING CARBOHYDRATE ON CD-43 AND CEA EXPRESSED IN CANCERIGENE CELLS AND METHODS OF USE OF THE SAME. The present invention provides novel antibodies that specifically bind to an epitope on CD43 or CEA expressed by non-hematopoietic cancer cells, but do not specifically bind to a leukocyte or Jurkat cell expressed CD43 and is capable of inducing apoptosis of cells. non-haematopoietic carcinogens following epitope binding on the cell surface of the non-haematopoietic cancer cell in the absence of cytotoxin conjugation and immune effector function, where the epitope comprises a carbohydrate structure and antibody binding to the epitope is inhibited by a carbohydrate comprising it. a Le? a? structure, a Le? a lactose structure, a LNDFH II structure or an LNT structure. In addition, the present invention also provides the use of the antibodies described herein for diagnostic and therapeutic purposes. |
| priorityDate |
2006-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |