abstract |
METHOD FOR TREATING A PAIN DISORDER IN A HUMAN. treatment of pain disorders with (IR, 4s) -trans 4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydro-1-naphthalenamine is described; and (1S, 4R) -trans 4- (3,4-dichlorophenyl) -1,2,3,4-tetraido-1-naphthalenamine. A process to prepare 4- (3,4-dichlorophenyl) -1,2, 3,4-tetraido-1-naphthalenamine is also described. The process includes preparing all four isomers of N- [4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydronaphthalen-1-yl] formamide, which are also useful in the treatment of pain disorders . |