http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-PI0712347-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2007-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80bf46bd176e0bef7f9a317e97fe78c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d9af77aca5f5ac48833873134fe7c55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a38d98c1d02b809e831910279c919d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5ba46115a984b90e37ff0bdb2eeb374 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38a61045fdde70d96bd9778de3e49709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c615d9f718c5e65ecf3a300bb4883884 |
| publicationDate | 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-PI0712347-A2 |
| titleOfInvention | pyrrolidine derivatives useful as bace inhibitors |
| abstract | PIRROLIDIN DERIVATIVES USEFUL AS FACE INHIBITORS. New pyrrolidine compounds 3-mono-, 3,4-di- and 3,4,4, -trisubstituted, these compounds for use in the diagnostic and therapeutic treatment of a homeothermic animal, especially for the treatment of a disease (= disorder) which depends on beta-secretase activity and / or beta-amyloid eration and subsequent aggregation in oligomers and fibrils; the use of a compound of this class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on the activity of beta-secretase and / or the generation of beta-amyloid and the subsequent aggregation in oligomers and fibrils; the use of a compound of this class in the treatment of a disease, which depends on the activity of beta-secretase and / or the generation of beta-amyloid and the subsequent aggregation in oligomers and fibrils; pharmaceutical formulations comprising a substituted pyrrolidine compound and / or a treatment method comprising administering said substituted pyrrolidine compound. The substituted pyrrolidine compounds are especially of the formula 1, wherein the substituents are as defined in the specification. |
| priorityDate | 2006-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 407.