| abstract |
<B> PROSTAGLANDINE AGONISTS EP ~ 4 ~ <D>. The present invention relates to a compound comprising a prodrug of an EP ~ 4 ~ prostaglandin agonist, wherein said prodrug is an ester, ether, or amide of an amino acid is described herein. Maintenance of the colonic mucosal barrier by a method comprising administering a therapeutically effective amount of an EP4 prostaglandin agonist to a colon of a mammal is also described herein. Dosage forms, medicaments, and compositions related to it are also described. |