| abstract |
SULPHURED DERIVATIVES OF CYCLIC UREA, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE AS KINASE INHIBITORS. The present invention relates to novel products of formula (I) wherein n represents the integer 0 or 2, R represents a pyridyl or pyrimidinyl radical substituted by a radical NR1R2, one of R1 and R2 represents hydrogen or alkyl and another of R 1 and R 2 represents hydrogen or optionally substituted alkyl, cycloalkyl, heterocycloalkyl, phenyl, pyrimidine, pyridyl, and CO-R 3 with R 3 selected notably from the amino, alkoxy, heterocycloalkyl, aryl, aryloxy and heteroaryl radicals; all of these radicals being eventually substituted; and salts thereof. |