| abstract |
<B> ORGANIC COMPOUNDS. <D> The present invention provides a compound of formula (I): said compound is an aldosterone synthase inhibitor, and thus can be used for the treatment of an aldosterone-mediated disorder or disease synthase. Consequently, the compound of formula I can be used in the treatment of hypokalemia, hypertension, congestive heart failure, renal failure, in particular, chronic renal failure, restenosis, atherosclerosis, syndrome X, obesity, nephropathy, post myocardial infarction, coronary heart disease , increased collagen formation, cardiac fibrosis and remodeling following hypertension and endothelial dysfunction. Finally, the present invention also provides a pharmaceutical composition. |