| abstract |
ALPHABLE TUMOR NECROSIS FACTOR INHIBITORS AND THEIR USE IN THE TREATMENT OF HUMAN DISEASES. Tumor necrosis factor alpha inhibitors are provided, which are useful in the treatment of a variety of disorders, including the treatment of pathological conditions associated with tumor necrosis factor alpha. Tumor necrosis factor alpha inhibitors have the following structures: including stereoisomers, pharmaceutically acceptable salts, and solvates thereof, where the substituents are as defined herein. Compositions containing an inhibitor of tumor necrosis factor alpha in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for using it. |