| abstract |
CYCLIC ALKYLAMINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND p53. The present invention relates to compounds of formula (I), their application as an inhibitor of a p53-MDM2 interaction, as well as pharmaceutical compositions comprising the compounds of formula (I), wherein n, m, p, t, R ^ 1 ^, R ^ 2 ^, R ^ 3 ^, R ^ 4 ^, R ^ 5 ^, R ^ 6 ^, R ^ 7 ^, Q, Y and Z have the defined meanings. |