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filingDate 2007-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_755eff415a5a08ac41c24eb5250b7983
publicationDate 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-PI0708849-B1
titleOfInvention Methods for the preparation of complex multivalent immunogenic conjugates, said conjugates, and pharmaceutical compositions
abstract methods for preparing complex multivalent immunogenic conjugates to said conjugates, and pharmaceutical compositions. The present invention relates to methods for the preparation of complex multivalent immunogenic conjugates which include the simultaneous reaction of several distinct immunogenic polysaccharides with at least one protein to produce the complex multivalent immunogenic conjugates. the simultaneous reaction involves the reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant.
priorityDate 2006-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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