| abstract |
PI-3 KINASE INHIBITORS AND METHODS OF USE FostatidylinositO (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the novel compounds, alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the novel compounds, alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by abnormal activity of growth factors, serine / threonine protein cjuinases, phospholipid kinases, protein G-linked receptors and phosphatases. |