| abstract |
TIADIAZOL DERIVATIVES FOR TREATMENT OF NEURODEGENERATIVE DISEASES. The present invention relates to specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment of an α-synucleopathy, such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. |