| abstract |
IMIDAZOL DERIVATIVES, COMPOSITIONS, AND SUBSTITUTED METHODS OF USE AS PTPASE INHIBITORS. The present invention provides imidazole derivatives of Formula (I-IV), methods of this preparation, pharmaceutical compositions comprising the compounds of Formula (I-IV), and their use in the treatment of animal or human disorders. The compounds of the invention inhibit protein 1B tyrosine phosphatase and thus may be useful for the administration, treatment, control, or supplement treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes. |