| abstract |
CYCLEALKYLAMINES AS MONOAMIN RECAPTATION INHIBITORS. The invention relates to new cyclohexylamine derivatives and their use in the treatment and / or prevention of disorders of the central nervous system (CNS) such as, for example, depression, anxiety, schizophrenia and sleep disorder, as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting the resorption of endogenous monoamines such as dopamine, serotonin and norepinephrine through the synaptic cleft, and methods for modulating one or more transporters of monoamine. |