| abstract |
CONDENSED PYRIDINE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME, AS WELL AS ITS USES. The present invention provides a compound of formula (1) having excellent JAK3 inhibiting activity and being useful as an active ingredient of an agent for treating and / or preventing various immune diseases, including autoimmune diseases, inflammatory diseases and allergic diseases. . The compound according to the present invention has an inhibitory activity against JAK3 and is therefore useful as an active ingredient of an agent for treating or preventing diseases caused by undesirable cytokine signal transmission (e.g., rejection during transplantation). organ / tissue disease, autoimmune diseases, multiple sclerosis, rheumatoid arthritis, psoriasis, asthma, atopic dermatitis, Alzheimer's disease, and atherosclerotic disease) or diseases caused by abnormal cytokine signal transmission (eg, cancer and leukemia). |