abstract |
COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE OF A COMPOUND. The present invention relates generally to the field of binders for nicotinic acetylcholine receptors (nAChR), the activation of nAChRs receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic receptors, especially of the brain. In addition, the present invention relates to new compounds (indazoles and benzothiazoles), which act as binders for the <244> 7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods their use. |