abstract |
<UM> FRONUROPEPTIDE-2 AGONIST, PHARMACEUTICAL FORMULATIONS, NEUROPEPTIDE-2 RECEPTOR AGONIST USE AND METHOD OF TREATING A DISEASE MODULATED BY NEUROPEPTIDE-2 AGONISTS <MV>. Neuropeptide-2 receptor agonists of formula (I) are provided: YR ~ 1 ~ -R ~ 2 ~ -XR ~ 3 ~ -R ~ 4 ~ -R ~ 5 ~ -R ~ 6 ~ -R ~ 7 ~ -R ~ 8 ~ -R ~ 9 ~ -R ~ 10 ~ -R ~ 11 ~ -R ~ 12 ~ -R ~ 13 ~ -R ~ 14 ~ -NH ~ 2 ~ (I). As well as their pharmaceutically acceptable salts, derivatives, fragments, in which the substituents are those described in the present invention. These compounds and pharmaceutical compositions are useful for the treatment of diseases such as, for example, obesity and diabetes. |